Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism
Kenneth Rosenfield·Stavros V. Konstantinides·Andi Tego·Markus Theurl·Gautam Visveswaran·Jan Albert Vos·Michael N. Young·Federico M Asch·Frederikus A. Klok·Gregory Piazza·Andrew Sharp·Fionnuala Ní Áinle·Michael R. Jaff·Stefano Barco·Samuel Z. Goldhaber·N Kucher·Iréne Lang·Irene Schmidtmann·Keith M. Sterling·Aleksander Araszkiewicz·V. Arora·Rafael Cires-Drouet·J G Coghlan·Lukas Hobohm·Wulf Ito·Kurt Jacobson·Christoph Kaiser·Grzegorz Kopeć·K Marx·Samuel McElwee·N Meneveau·Peter Monteleone·Jose M. Montero-Cabezas·Christoph B. Olivier·Marek Roik·John Park·Rahul Sakhuja
In patients with acute, intermediate-risk pulmonary embolism, ultrasound-facilitated, catheter-directed fibrinolysis plus anticoagulation led to a lower risk of the composite of pulmonary embolism-related death, cardiopulmonary decompensation or collapse, or symptomatic recurrence of pulmonary embolism within 7 days than anticoagulation alone. (Funded by Boston Scientific; HI-PEITHO ClinicalTrials.gov number, NCT04790370.).