The Impact of Cytomegalovirus Reactivation on Cytomegalovirus-Specific Immune Reconstitution in Hematopoietic Stem Cell Transplant Recipients Receiving LMV Prophylaxis

Abstract Background Cytomegalovirus (CMV) remains the most common viral infection after hematopoietic stem cell transplantation (HSCT).The clinical significance of different CMV DNA forms remains unclear, particularly regarding CMV-specific immune reconstitution. Methods A total of 76 HSCT recipients were enrolled. A quantitative DNase I–resistant CMV-DNA assay was performed to distinguish infectious from non-infectious CMV DNA. Based on DNase treatment results, patients were divided into three