CCHEST Journal3/1/2026

Cone Beam Computed Tomography-Guided Bronchoscopy versus Computed Tomography-Guided Transthoracic Needle Biopsy for Peripheral Pulmonary Lesion Diagnosis

CBCT-GB demonstrated a 24-month diagnostic accuracy comparable to CT-TTNB while offering improved safety and concurrent mediastinal lymph node staging. This data supports CBCT-GB as the optimal initial procedure for PPL diagnosis.