Intensification of media components can effectively improve biochemical production by reinforcing the metabolic capacity of engineered strains. Here, we present a citrate-enabled medium intensification strategy for sustainable l-theanine biomanufacturing in Corynebacterium glutamicum. Recombinant strains expressing heterologous theanine synthases were constructed using a strain expressing l-glutamate-l-cysteine ligase from Escherichia coli (THE-6) to achieve high theanine production. To establis
Citrate-enabled process intensification reinforces energy and redox metabolism for sustainable bioproduction using Corynebacterium glutamicum
K. S. Park·Chan-Duck Jung·June-Ho Choi·Young Joo Yeon·SunJoo Park·Jiyoung Park·Yunjeong Song·Si Jae Park·Hoyong Kim·Kyungmoon Park·Dong Young Lee·Yung-Hun Yang·Yunhee Jeong·Hoe-Suk Lee
