Impact of Basal Ganglia Perivascular Spaces on Ischemic and Hemorrhagic Risks in Patients Taking Antithrombotic Therapies
Soya Iwamoto·Yasunari Niimi·Toshiki Mizuno·Sohei Yoshimura·Kanta Tanaka·Yoshikane Izawa·Shoji Arihiro·Masayuki Shiozawa·Akira Tsujino·Kuniaki Ogasawara·Yoshikazu Uesaka·Naoki Saji·Hideki Matsuoka·Yoshiki Yagita·Masafumi Ihara·Kohsuke Kudo·Masatoshi Koga·Jin Nakahara·Hirofumi Maruyama·Yoshinari Nagakane·Yasushi Takagi·Makoto Nakajima·Koichi Oki·Haruhiko Hoshino·Toru Iwama·Kazutoshi Nishiyama·Hiroyuki Daida·Ryosuke Doijiri·Norifumi Metoki·Kaori Miwa·Takao Kanzawa·Toshiyuki Uehara·Yasuo Iwasaki·Hikaru Nagasawa·Shigeru Fujimoto·Shinichi Yoshimura·Tatsuya Ishikawa·Masafumi Otaki·for the BAT2 Investigators·Toshihiro Ueda·Yasuhiro Hasegawa·Hiroshi Yamagami·Kenji Kamiyama·Teruyuki Hirano·Shinichi Takahashi·Keizo Yasui·Takeshi Yamada·Yukako Yazawa·Daisuke Takahashi·Satoshi Okuda·Kazunori Toyoda·Kazumi Kimura·Yasushi Okada·Arakawa Shuji·Tadashi Terasaki·Makoto Sasaki·Yasuhiro Ito·Nobuyuki Sakai·Yasuyuki Iguchi·Yusuke Yakushiji·Rei Kondo
Higher BGPVS burdens are associated with higher risks of ischemic stroke and major bleeding in patients receiving antithrombotic therapy. BGPVSs may serve as useful imaging biomarkers for vascular risk assessment and personalized therapy.