This study redefines TSR assessment, shifting from manual estimation to high-dimensional semantic reasoning. By identifying the non-linear prognostic mechanics of the stroma, our token-guided framework offers a biologically interpretable solution for HCC. We suggest that the future of computational pathology may lie not in simple quantification, but in the semantic fusion of human domain knowledge with AI reasoning.
Token-guided multimodal prognosis in hepatocellular carcinoma: a framework steered by tumour–stroma ratio
Heyu Huang·Guo-Yue Lv·Yuguo Chen·Liang Guo·Meishan Jin·Limei Qu·Junfeng Ye·Yang Zheng·Mingyue Li·Ke Wu·Y. L. Zhao·Meng Wang·Feng Wei·Zhong-Qi Fan·Yu Huang·Ping Zhang·Xiao-Dong Sun·Xiao-Ju Shi·Feng-Ying Xie·Alfred Wei Chieh Kow·Chuan-Hao Hu·Wei Qiu
