Nuclear Receptors as Orchestrators of Regulatory Cell Death

Recently, a growing number of novel types of regulated cell death have been reported, including pyroptosis, necroptosis, and ferroptosis, among others. These types of cell death play crucial roles in a wide array of physiological functions such as metabolism, tissue injury and repair, chronic disease progression, and immune protection. However, specifically targeting cell death pathways for therapeutic purposes remains a challenge due to the unresolved complexities in pharmacological interventio