Soft-interfaced liquid crystal microfluidics can probe the rigidity of lipid vesicles

Abstract Liquid crystal (LC)-aqueous interfaces were shown to respond to the phospholipid interactions via optically observable ordering transitions; however, past attempts lack the quantification of the transport and fusion kinetics of the vesicles at the interfaces. Herein, we investigated the response of flowing LC-aqueous interfaces upon fusion of the vesicles formed by pure 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), 1,2-dipalmitoyl-sn-