Cultural engagement (e.g., going to live music events and theater performances, museums, galleries and exhibitions, and the cinema) is longitudinally associated in repeated epidemiological studies with age-related mental and physical health outcomes. However, it is unclear whether it also influences how fast older adults age physiologically-so-called age acceleration. This study aimed to ascertain whether regular cultural engagement among older adults is related to slower physiological aging using a previously derived physiological age index and a doubly robust estimation approach to account for confounders. Using older adults from the English Longitudinal Study of Ageing (n = 4467), we found that cultural engagement was related to lower physiological age cross-sectionally (average treatment effect -2.17; 95% CI -3.48 to -0.86) and 4 and 8 years later. The effect was seen consistently for all three types of cultural activity explored (cultural performances, museums/exhibitions, and the cinema). These analyses were robust to multiple sensitivity analyses, including considering alternative confounding structures, outliers, and treatment specification. Overall, these findings provide insight into how cultural engagement may be related to processes of aging.