Advances in vehicles for in situ delivery: From classical vectors to biologically inspired structures

The emerging fields of synthetic biology and gene therapy rely on delivery systems to introduce the nucleic acids and proteins into recipient cells. Hence, the development of delivery tools with high specificity, strong manufacturability, and low immunogenicity can advance these fields. In this review, we summarize recent advances in the development of delivery systems for proteins and nucleic acids. First, we outline viral vector-based delivery tools, including lentivirus, adenovirus, and adeno