Genomic estimates of Identity-By-Descent relationships in large scale data sets

An approximate computationally efficient multipoint linkage analysis algorithm was developed to estimate unbiased IBD-based relationship and inbreeding coefficients. Its unbiasedness and precise definition of the base population makes it well suited for the genomic management of inbreeding and genomic optimal contribution selection. In addition, G_la based optimal contribution selection is neutral with respect to allele frequency changes.