Introduction: Obesity is an emerging public health challenge in low-income countries undergoing rapid nutritional and socio-economic transition. Local analytical evidence remains limited in Burundi. Methodology: An analytical case-control study was conducted by involving 90 participants, including 30 obese cases (BMI ≥ 30 kg/m²) and 60 normal-weight controls (BMI 18.5-24.9 kg/m²). Data were collected using structured questionnaires, anthropometric measurements (weight, height, BMI), blood pressu