In the bacterial world, riboregulation is extremely widespread and controls virtually all aspects of the life of bacterial cells. Riboregulatory mechanisms are very diverse and involve trans- and cis-acting regulatory elements such as small RNAs and riboswitches that are able to control gene expression by direct binding of small molecules. Here, we report a very peculiar and rare example of riboregulation in which an mRNA is regulated by both trans-acting sibling sRNAs and a