Efficacy of Acupuncture for Prurigo Nodularis: A Protocol for Systematic Review and Meta-analysis

Background: Prurigo nodularis (PN) is a chronic inflammatory skin disease characterized by severe pruritus, significantly impairing patients’ quality of life and work capacity. Acupuncture has emerged as a promising therapeutic option, with a growing body of research demonstrating its notable efficacy in treating this condition. However, the mechanisms involved remain unclear, and current evidence lacks integration to help clinical decisions. This study initiates the first systematic evaluation