Association of sleep disturbance during breast cancer treatment and left ventricular ejection fraction decline: a prospective cohort study
Warren Szewczyk·W. Gregory Hundley·Bonnie Ky·A. Ladd·Kerryn W. Reding·Kathryn E. Weaver·Kristine Olson·Oxana Palesh·Ralph B. D’Agostino·Richard K. Cheng
Sleep disturbances during breast cancer (BC) treatment may represent a modifiable contributor to left ventricular ejection fraction (LVEF) decline during BC treatment. We investigated the association of sleep disturbance and LVEF decline in a prospective cohort of 247 women with non-metastatic BC scheduled for chemotherapy as part of the UPBEAT study conducted through the Wake Forest NCI Community Oncology Research Program Research Base (WF NCORP RB; WF-97415, UG1CA189824). Participants complete