Methodological discordance between apical four-chamber and biplane Simpson’s method for left ventricular ejection fraction: a retrospective study of a credentialed echocardiographic dataset
Hasan Burak İşleyen·Mahsa KHANMOHAMMADİ·S. Bulut·Fatih Kızkapan·Cevahir Alioglu·Necla Zeynep Eren·Ali Arda Sozen·Sevil Tugrul Yavuz
Abstract Background Left ventricular ejection fraction (LVEF) remains central to heart failure phenotyping and device-based decision-making, yet the degree to which apical four-chamber (A4C) and biplane Simpson measurements diverge at clinically actionable thresholds is not well defined. Methods We analysed 1,022 unique algorithmically derived echocardiographic studies from 784 patients in the credentialed MIMIC-IV-ECHO-Ext-LVVOLUMES-A4C-ROI resource. Each study contained paired A4C and biplane