BBMC Surgery4/24/2026

Predictive value of biochemical markers and clinical scoring systems for outcomes in nonagenarians and centenarians admitted to the ICU after cholecystectomy for acute cholecystitis: a binational multicenter analysis

With the global rise in nonagenarian and centenarian populations, demand for surgical and critical care in this age group is increasing. Acute biliary disease, particularly cholecystitis, often necessitates surgery, yet outcomes following cholecystectomy in the oldest-old ICU patients remain poorly characterized. This study aimed to identify clinical and biochemical predictors of mortality and resource use in this cohort. In this retrospective binational cohort study, we used the Australian and