Histological evaluation of fascicular damage following repeated sciatic nerve transfixion: an anatomical study

Ultrasound guidance has improved the accuracy and safety of peripheral nerve blocks, yet intraneural and even intrafascicular needle placement remains possible. The true incidence of fascicular injury after direct nerve transfixion is uncertain due to limited histological data. This study aimed to determine the frequency of fascicular damage after needle transfixion of the sciatic nerve using a human anatomical model. A sciatic nerve segment was harvested from a fresh-frozen male cadaver without