Comparative profiling of virulence determinants, capsular serotypes, and antimicrobial resistance in hypervirulent and classical Klebsiella pneumoniae isolates from liver abscess patients

This study aimed to compare the virulence and resistance gene profiles, capsular serotypes, and molecular epidemiology of hypervirulent Klebsiella pneumoniae (hvKP) and classical Klebsiella pneumoniae (cKP) strains isolated from patients with liver abscesses in China, and to evaluate their phenotypic virulence using in vitro and in vivo models. A total of 83 non-repetitive K. pneumoniae strains were collected from liver abscess patients between January 2023 and December 2024. Strains positive fo