The melt oxidation of isotactic polypropylene (iPP) was used to impart functionality relevant for upcycling and repurposing the polymer for new applications. Terminal vinylidene groups (due to chain scission) and oxidized functional groups such as ketones, aldehydes, and hydroxyl groups were present in the melt oxidized samples, forming PP copolymers with functional co-repeat units. Two regimes were identified: a scission regime that occurred in which chain molecular weight was reduced with only