The regulation mechanism of α-linolenic acid bioavailability by flaxseed lignan macromolecules in O/W emulsions

Enhanced α-linolenic acid (ALA) intake effectively alleviates population sub-health status through dietary pattern modification, demonstrating substantial implications for promoting national health advancement. In this study, the multi-targeted regulation on ALA micellization, absorption, and lymphatic transport by natural flaxseed lignan macromolecules (FLM) and its thermal treatment products (FLM 150) was systematically investigated in an emulsion delivery system. In vitro Caco-2 transport ass