A bstract In this paper, we propose two novel signatures of Higgs decays to search for electron-muon flavor violation. These signatures arise from the presence of a light pseudoscalar into which the 125-GeV Higgs boson decays. The pseudoscalar subsequently decays into an electron-muon pair, leading to multilepton final states, which are relatively clean signatures to search for at the LHC. As a benchmark, we consider the type-III Two-Higgs-doublet-model. We analyze both low-energy and collider c