Reframing gestational diabetes mellitus through two new paradigms: Early detection and lifelong intergenerational follow‐up
M. S. Rudge·Luis Sobrevía·Danielle Cristina Honório França·Katherin Silva·Iracema Mattos Paranhos Calderon·Roberto Araújo Costa·Cláudia Garcia Magalhães
Gestational diabetes mellitus (GDM) has traditionally been regarded as a transient metabolic disorder limited to pregnancy, with management directed primarily towards reducing obstetric and perinatal complications. Yet a growing body of evidence over the past two decades compels a fundamental redefinition. Two emerging paradigms expand the physiological and clinical understanding of GDM. The first recognizes early-onset GDM (e-GDM), diagnosed in the first trimester, as a severe metabolic phenoty
