Accessible data collection methods in clinical trials: do current best practices for the implementation of electronic patient-reported outcome measures (ePROMs) meet accessibility standards?

Apps and web browsers, whether on smartphones, tablets or laptops, have become the mainstream methods of capturing clinical outcome assessment (COA) data, and patient-reported outcome measures (PROMs) in particular, in clinical trials. There has long been concern around whether implementing traditionally paper-based questionnaires on electronic systems may impact the measurement properties of these carefully validated questionnaires, with migration best practices focusing predominately on this i