Development of striated muscle microvasculature across the perinatal period in lambs
Eileen I. Chang·Laura D. Brown·Sonnet S. Jonker·T. Neil Dear·Emma F. Saunders·Jane Stremming·Samantha Louey·Holland Stacey·Evgenia Dobrinskikh·Dana Strode·Saif I. Al‐Juboori·Sreya Varanasi·Collin Painter
Transition of the fetus to extrauterine life requires increased cardiac workload and skeletal muscle activity, yet little is known about microvasculature growth during the perinatal period. We collected hindlimb skeletal muscles and cardiac left (LV) and right ventricles (RV) from fetal (135 days of gestational age; 135D) and neonatal (postnatal days 1 and 5; PD1 and PD5) lambs to measure vascular structures by immunofluorescence and expression of angiogenesis regulators. Heart and skeletal musc