Use of ctDNA in Older Women with ER+ Breast Cancer to Facilitate Surgical De-escalation: A Prospective, Hybrid-Decentralized Trial with Correlative Studies
Neil Carleton·P. F. McAuliffe·Quratulain Sabih·Monica Malhotra·Kristin Lupinacci·Adrian V. Lee·Tanner J. Freeman·Fangyuan Chen·Michael S. Cowher·Catherine Bridges·Emilia J. Diego·Marija Balić·Amanda Laubenthal·Antony Tin·Hunter Waltermire·Marion Joy·Vikram Gorantla·Ronald R. Johnson·S. L. Puhalla·R. Bhargava·A. Chang·Ekaterina Kalashnikova·Steffi Oesterreich·Minetta C. Liu·Angel Rodriguez·Julia Foldi
These findings suggest that ctDNA may be a modality to identify older patients who can safely receive long-term pET, warranting future evaluation in a randomized setting.