From Type 2 Diabetes Mellitus To Diabetic Cardiomyopathy – A Systematic Review On The Role Of MicroRNA
Anna Żarek-Starzewska·Marek Kuch·Maciej Janiszewski·Grażyna Sygitowicz·Amelia Joanna Mądrecka·Dominika Klimczak‐Tomaniak
MicroRNAs, short single-stranded non-coding RNAs, are key regulators of various pathophysiological processes in DCM. By modulating gene expression, they influence critical signaling pathways involved in inflammation, apoptosis, pyroptosis, oxidative stress, and fibrosis, all of which contribute to DCM progression. Emerging research suggests that miRNAs could serve as early-stage biomarkers for asymptomatic DCM and may offer novel therapeutic targets. This systematic review compiles current findi