Neural Responses to Affective and Cognitive Theory of Mind in Children With Conduct Problems and Varying Levels of Callous-Unemotional Traits
Catherine L. Sebastian·Essi Viding·Patricia Lockwood·Stéphane A. De Brito·Eamon McCrory·Charlotte A. M. Cecil·Nathalie M. G. Fontaine
Childhood conduct problems are associated with amygdala and anterior insula hypoactivity during a complex affective processing task including an empathy component. Suppressor effects between conduct problems and callous-unemotional traits in the amygdala suggest a potential neural substrate for heterogeneity in affective profiles associated with conduct problems.